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Distributable and reproducible record in the format of an R package for the research presented in:

Filer DL, Hoffman K, Sargis RM, Trasande L, Kassotis CD. On the utility of ToxCast-based predictive models to evaluate potential metabolic disruption by environmental chemicals. 2022. Environmental Health Perspectives (provisionally accepted).

The analysis is replicated within 3 vignettes, published freely here.

Additionally, the specific figures and supplemental tables included in the paper are created by two scripts, ‘makeFigs.R’ and ‘makeSuppTables.R’ in the above ‘inst’ directory.


if (!require(remotes)) install.packages("remotes")
                        dependencies = TRUE, 
                        build_vignettes = TRUE)